منابع مشابه
Airway mucus.
Hypersecretion of mucus is a cardinal sign of airways inflammation. Normally, secretion of mucus is designed to protect the respiratory portion of the lung from injury, but in disease its chronic overproduction in large airways (bronchi) and its appearance in small conducting airways (bronchioles) may be detrimental. Its relevance to patient discomfort and infection is generally accepted, but i...
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The ability of mucus to function as a protective barrier at mucosal surfaces rests on its viscous and elastic properties, which are not well understood at length scales relevant to pathogens and ultrafine environmental particles. Here we report that fresh, undiluted human cervicovaginal mucus (CVM) transitions from an impermeable elastic barrier to non-adhesive objects sized 1 microm and larger...
متن کاملBiological modeling of mucus to modulate mucus barriers.
A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.
متن کاملBronchial Mucus Transport
Effective clearance of inhaled particles requires mucus production and continuous mucus transport from the lower airways to the oropharynx. Mucus production takes place mainly in the peripheral airways. Mucus transport is achieved by the action of the ciliated cells that cover the inner surface of the airways (mucociliary transport) and by expiratory airflow. The capacity for mucociliary transp...
متن کاملLactobacillus Adhesion to Mucus
Mucus provides protective functions in the gastrointestinal tract and plays an important role in the adhesion of microorganisms to host surfaces. Mucin glycoproteins polymerize, forming a framework to which certain microbial populations can adhere, including probiotic Lactobacillus species. Numerous mechanisms for adhesion to mucus have been discovered in lactobacilli, including partially chara...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1967
ISSN: 0035-9157
DOI: 10.1177/003591576706000136